ALPHA GPC
Improves Mental Performance
The quality of our life experience - and our ability to live life to the fullest
- is a direct result of optimal brain function. Only a few years ago, nothing
could be done to stem the tide of poor circulation, forgetfulness and "mental
fog." But neurological science exploration has identified a fundamental
brain compound critical to attention, learning, memory, and even the higher
cognitive functions of reasoning and intuition.
Research confirms that L-alpha-glycerylphosphorylcholine (called Alpha-GPC for
convenience) is crucial to neuronal function and structure. Derived from purified
soy lecithin, Source Naturals ALPHA-GPC readily converts to acetylcholine in
the brain, helping to maintain neuronal structure integrity. Source Naturals
provides an easy and convenient means to profoundly impact the very nexus of
our body and mind.
GPC Is Unique
No other nutritional compound comes close to GPC in its ability to boost critically
important acetylcholine levels. Found in both the brain and the peripheral nervous
system (including the nerve-muscle junctions), acetylcholine is a key nerve
messenger molecule, or neurotransmitter. Aging brains are characterized by functional
deficiencies in both acetylcholine and its cholinergic receptors. GPC is a highly
bioavailable supplement that boosts acetylcholine levels to improve cognitive
function. It is also a major choline reservoir, helping to protect the brain
against damage from poor circulation and potentially toxic metabolites.
Deficiencies in acetylcholine can cause the body to break down phosphatidylcholine
for its choline content, leading to the death of brain cells. Yet in controlled
clinical trials of middle-aged subjects taking GPC, reaction time was enhanced
and there was improved energy generation and electrical coordination in the
brain. For older subjects, double-blind trials demonstrated that GPC had superior
benefits over certain other brain nutrients for mental focus, recall, verbal
fluency - a unique, marked overall enhancement of mental performance.
GPC is an example of what the great Linus Pauling referred to as "orthomolecules,"
that is, molecules that are "orthodox" or "correct" for
the body. GPC excels as a protective nutraceutical for memory loss and mood
enhancement. It protects cells of the brain (and other organs) from damage,
shielding a range of important biomolecules against toxin build-up.
Extensive Clinical Testing
In clinical trials that involved more than 5,000 patients, GPC showed marked
improvement in overall brain performance. Depending on the particular trial,
50-70 percent of the patients who received GPC had their mental functions improved
to a degree "meaningful to life quality." GPC has shown revitalizing
effects on the declining brain, and preliminary evidence suggests GPC may act
on the pituitary gland to partially restore its capacity to make growth hormone,
vital for cell maintenance and longevity.
Other unique brain features of GPC are its benefits for attention and recall
in young healthy adults, and its superior bioavailability. GPC readily crosses
the bloodbrain barrier to raise brain choline levels within a few hours following
oral intake. GPC helps with body-mind integration by being a ready reservoir
for acetylcholine. This neurotransmitter is ubiquitous in brain circuit maturation,
expansion, renewal and repair, as well as in the
"agility" or adjustments of the circuitry that occur during adult
life.
In addition, an animal study has shown that GPC increases the release of GABA
(gamma-aminobutyric acid), the most important and abundant inhibitory neurotransmitter
in the brain. It acts as a "balancer" for the brain and helps induce
relaxation and sleep. Without sufficient GABA, neurons fire at random, unable
to make sense of incoming signals. GABA helps minimize "neural noise,"
making it easier to focus and concentrate.
Why you should take GPC:
- Mental performance is improved at all ages (including attention, concentration
and recall).
- GPC supports mind-body focus, including reflexes, response time, and endurance.
- GPC has benefits for healthy aging, such as growth hormone release.
- GPC protects all the body's cells through its unique osmolyte capacities.
- GPC is naturally present in very high concentrations in healthy cells, and
also in mother's milk, where it is the major source of choline for the developing
brain.
While it may be the single best nutrient for the brain, GPC is also a broader
supplement for active living and healthy aging because it supports optimal metabolic
function in all the organs. GPC has a metabolically privileged relationship
with DHA (docosahexaenoic acid, omega-3). These are combined to make cell membrane
phospholipids essential to metabolic efficiency in kidney, liver, and muscle
function, and for sperm maturation. These body-wide functions, combined with
its known brain benefits, allow GPC to support the functional integration of
the brain with the other organs.
Don't pass up this newly discovered option to enhance the quality of your life,
health and higher mental functions. Explore your nearby natural food outlet
and utilize discoveries such as GPC, which has already improved the health and
chances of longevity for the millions who have been wise enough to join the
Wellness Revolution.
References:
Parnetti L, Amenta F, Gallai V. 2001. Choline alfoscerate in cognitive decline
and in acute cerebrovascular disease: an analysis of published clinical data.
Mechs Aging Dev. 22: 2041.
Canal N, et al. 1993. Comparison of the effects of pretreatment with choline
alfoscerate, idebenone, aniracetam and placebo on scopolamine-induced amnesia.
Le Basi Raz Ter. 23: 102.
De Jesus Moreno Moreno M. 2002. Cognitive improvement in mild to moderate Alzheimer's
dementia after treatment with the acetylcholine precursor choline alfoscerate:
a multicenter, doubleblind, randomized, placebo-controlled trial. Clin Ther.
25: 178.
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